Fish oils may help to activate anti-diabetic genes
Polyunsaturated fatty acid fish oils may activate genes that regulate fat cell differentiation and glucose homeostasis, according to new research on mice.
The new study published in Journal of Nutritional Biochemistry suggests supplementation with fish oils activates the transcription factor PPARγ, increasing regulation of adipocytes and helps to maintain glucose homeostasis.
“We demonstrated that adipogenic genes and glucose metabolism genes were elevated in PPARγ transgenic mice when fed fish oil. This transgenic mouse model provided direct evidence to demonstrate PUFA, especially EPA and DHA, regulate glucose homeostasis through interaction with PPARγ,” wrote the researchers, led by Dr Yu-Hsiang Yu from the National Taiwan University.