Home » Immunity, Inflammation, Respiratory Allergies

Butterbur Extract Shows Promise for Allergic Rhinitis

Submitted by on March 31, 2011 – 4:10 pm | 1,820 views

Butterbur (Petasites hybridus [L.] P. Gaertn. et al., Asteraceae) is a perennial herb native to northern temperate regions that exists in two chemo-varieties: those containing petasins and those with furano-petasins. In terms of safety and efficacy, the petasin chemo-variety appears to be superior to the furano-petasin chemo-variety. Therefore, leaves from one selected petasin chemo-variety (PETZEL) are cultivated and dried to produce the extract Ze 339 (Tesalin®; Zeller Medical AG, Switzerland). This extract has anti-inflammatory properties and is composed primarily of petasins and fatty acids; aromatic compounds and phytosterols are also present. Petasins are bioavailable and have a half-life of 4–6 hours (half-life: the time required for the concentration of petasins in the blood to be metabolized and reduced to half the original level, thereby reducing or terminating its pharmacological activity).

Read the complete article on acuatlanta.net