Licorice is one of the most extensively researched medicinal and food plants.1 Studies on licorice have demonstrated positive effects for treatment of various types of ulcers and chemoprevention.6 Other studies indicate the following: (1) dietary consumption of licorice root extract may help to lower cholesterol and act as an antioxidant,6,7 (2) compounds in licorice inhibit serotonin re-uptake and may be useful in the treatment of mild to moderate depression in women,8 and (3) licorice may help reduce body fat mass.9 One study suggests that topical application of licorice extract may be effective in treating the itching and inflammation associated with dermatitis.10

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